Monday, 31 December 2012

China & research

It is reported China has experienced the strongest growth in scientific research over the past three decades & it’s not slowing down. It is only second place to the US now. And if it continues like this, it will be the largest producer of scientific knowledge by 2020.

Experts in the field said China is out on its own, far ahead of the pack. Although its quality remains mixed, Chinese research has also become more collaborative, with almost 9 per cent of papers originating in China having at least one US-based co-author.
The Thomson Reuters figures show not only the “awe-inspiring” expansion of Chinese science but also a very powerful performance by Brazil, much slower growth in India and relative decline in Russia.
 Three main factors are driving Chinese research.
First is the government’s enormous investment, with funding increases far above the rate of inflation, at all levels of the system from schools to postgraduate research.
Second is the organised flow of knowledge from basic science to commercial applications.
Third is the efficient and flexible way in which China is tapping the expertise of its extensive scientific diaspora in north America and Europe, tempting back mid-career scientists with deals that allow them to spend part of the year working in the west and part in China.

Monday, 17 December 2012

Research using animals

Lately in Singapore, a national facility to provide large animals such as monkeys and pigs to research groups has been given the thumbs up, following an extensive feasibility study. We needed that as this  move will help speed up the development of new drugs and treatments, and take Singapore's biomedical capabilities up a notch.

Large animals are needed for such work because a compound that looks like a successful drug in the petri-dish or on a mouse might not work as well in larger creatures and humans. E.g. Before clinical trials on people, research on vaccines and diseases including glaucoma, myopia and HIV infection is carried out on monkeys such as macaques, which are genetically similar to humans.

Pigs, with their physiology and anatomy relatively similar to humans, are used to test new drugs and medical devices such as artificial knee joints and dental implants, and for surgical training. Generally, rats, mice and fish are used in experiments, although rabbits, dogs, pigs and monkeys are also used in some. Most are euthanised at the end of a trial.

But scientists say that while they continue to develop alternatives to animal testing, in many cases it is still impossible for a computer or test tube to substitute a complex biological system when studying a disease, vaccine or drug for efficacy and side effects. "Monkeys are more similar to us than mice, and pigs are closer in size. Sometimes, it's a necessary evil and there's no way around it."

“Such a facility will enhance Singapore's overall capability in translating discoveries to the clinic .  It will increase our strength in pre-clinical research such as drug discovery, drug development, testing of biomarkers and medical technology, prior to first-in-man studies”  said Professor Wong Tien Yin, group director of research at SingHealth , who is also executive director of the Singapore Eye Research Institute.
But research using animals has long been condemned by animal welfare groups. Thank goodness this is spore, we are probably more practical.....hahha... do we even have such groups active here?
 
 

Thursday, 13 December 2012

No more dyes?????

Researchers are in hot pursuit of a "cure" for gray hair—and they're getting closer.

 A study published last year showed that gray is caused by hydrogen peroxide and other cell-damaging molecules that build up as we age, bleaching color from the hair. The absence of an enzyme called catalase allows these molecules to accumulate, but EXT Life Sciences, a Michigan-based biotechnology company, believes it has found a chemical compound that can restore catalase and thus return hair to its original color.

 The company is working to incorporate the ingredient into leave-in conditioners and serums, says cofounder Stanley Terlecky, PhD, professor of pharmacology at Wayne State University School of Medicine.

 And across the Atlantic, L'Oréal's Paris-based hair biology research group recently identified a pair of genes that may determine the longevity of the cells that give hair its color. L'Oréal scientists are hard at work developing a treatment (either a pill or a topical formula) to block the progressive decline in these color-giving cells and stop—or at least slow—the graying process, says group director Bruno Bernard, PhD. Lets hope they make it!!!!

Tuesday, 4 December 2012

Christmas Shopping!!!!!

Went shopping today. Time to buy Christmas gifts for family & friends.

I'm lazy, so for the girls I'll get them perfume this year. Why? Because that cant go wrong. Just go for the most beautiful bottles & there are lots to choose from. Even if the scent is wrong or they hated it, no one can say no to a beautiful bottle....lol..... it's all about packageing!!!!

For guys ...hmm..... that's hard but I'll go with perfume also.....lol..... Come on, I've got not much time & dont particularly like shopping so....? Not very creative???? What you expect? They'll understand!!!

Saturday, 24 November 2012

Sea horses & dragons

Prior to these recent intersex discoveries in male frogs , only a few other male animal species demonstrated pregnancy. Probably most famous among these species is the male seahorse, which takes on a reproductive role that is opposite to what is most commonly seen in nature. Male seahorses compete with each other not to impregnate female seahorses but to be impregnated. During sea horse mating the female deposits unfertilized eggs into the male’s brood pouch. The male seahorse then fertilizes the eggs with his own sperm, thus initiating a three-week pregnancy that is marked by an inability to move around and search for food. After 3 days of labor, the male seahorse will give birth to 200 baby sea horses.

A member of the same Syngnathidae family as seahorses, male pipe fish also carry eggs in a protective pouch before giving birth. A few years back, researchers discovered a specific gene that supports the protective pouches and allows male pipefish pregnancies to occur. Called patristacin, this gene sustains male pipe fish pouches, which help regulate the amount of saline in the womb. Interesting but not surprising, the patristacin gene is also found in seahorses and even in the kidneys and livers of other bony fish.

There is more to the eye when it comes to the leafy sea dragon another relative to the seahorse. Not only looking like a piece of floating seaweed, the male leafy sea dragon cares for roughly 250 bright pink eggs that are attached to its tail via a long tube stemming from the female leafy sea dragon partner. After attaching to the male’s brood pouch, the eggs take nine weeks to hatch, changing in color to either purple or orange during this time period. When ready to give birth, the male leafy sea dragon shoots the baby sea dragons out of its tail during a 24-48 hour period. Only 5% of the leafy sea dragons survive, and those that do are pretty much independent from birth.

Beautiful Leafy Sea Dragon

Fascinating isnt it????

Friday, 19 October 2012

GreenCast: econ friendly walls

Never heard of this? Well you soon will... it's an invention -very local- born out of adversity!!!

Remember years back when neighboring countries  impose bans on sand exports to spore which drove up sand prices & construction cost. Well that lead to 2 outcomes, one:  developers switched to using glass as walls, not only it gives buildings & condos a more beautiful facade, it's cheaper!

The other was the Building & Construction Authority awarded a 1.2 million dollar R&D grant to NUS 's department of Civil engineering to  encourage development of technology that would make construction cheaper, greener & possibly faster.  Professor Wee Tiong Huan's team stood up for the challenge & GC ecoWall was born!!!!!! Together with a Realtor, Mr  Patrick Tan, they incorporated GreenCast 2 years ago in 2010.

So what's all the fuss about? Well to begin with, it's developed in Singapore....yay.....!!!!! Kudos to Professor Wee- That should be encouraged right?????  Not only is this new product more Eco-friendly, it is also more efficient! It's stronger than brick. Great for soundproofing. Installation is also simpler & faster leading to cost cutting verses the traditional cumbersome way of brick laying which is time consuming & costly.

So what's the future for GreenCast? Very Bright I hope.... as of this moment, they are targeting a turnover of 10 million dollars by the 2013 financial year. Good Luck guys.... very proud of the effort!!!

Saturday, 6 October 2012

Adult cells into Stem Cells

There's lots of excitement when UK John Gurdon of Gurdon Institute in Cambridge & Shinya Yamanaka of Kyoto University  won the Nobel prize in Medicine recently!!! They share the US $1.2 million .

Their research........... They found that adult cells can be turned back into stem cells! which can turn into any kind of tissue & may one day repair damaged organs!!!!!!! The big hope is for stem cells to be able to be used to replaced damaged tissue in EVERYTHING from spinal cord injuries to Parkinsons.

In the past scientist once thought it was impossible to turn adult tissue back to stem cells & stem cells could only be created by  harvesting embryos. Thanks to these 2 brilliant men, we know now that development is not strictly a one-way street. Can you imagine the possibilities now?????

Wednesday, 3 October 2012

Interested in looking at Einstein's Brain?

Oh Boy..... did you know that they have recently launched an exclusive iPad application of Einstein's brain!!!!! I'm serious! This will allow researchers & kapos like us to peer into his brain like looking through a microscope. Now I was wondering what would I do that for? hmm....

Apparently a medical museum had obtained funding to scan & digitize nearly 350 fragile & priceless slides made from slides of Einstein's brain after his death in 1955. A pathologist removed E's brain hoping that someone in the future could discover the secrets behind his genius.

Research showed that E's parietal lobe was 15 % wider than normal. This is the area that's impt to the understanding of maths, language & spatial relationships.

Tuesday, 18 September 2012

Congrats to Professor Zhan Baile

Ok for those of you who are not within our community, he's  NTU's assistant prof & he's recently named one of the world's top 35 young innovators under the age of 35, receiving the accolade from the MIT based Technology Review magazine.

He invented the "invisibility cloak".... haha... not the Harry Porter kind but this is real science/technology!!! The Technology Review Citation called Dr Zhang's technique a "'simple, promising solution.... while it has serious limitations... it does suggest a possible path to making practical invisibility cloaks,..." E.g. it could shrink cellphones & other electronics. Currently some elemnets in such devices must be separated becos of electromagnetic interference. but if you can make them " invisible to each other" , you can put them closer to each other!

Wednesday, 29 August 2012

Decided to go for monthly whitening jabs with Dr Keith Ong ...lol...

Just completed my last whitening jab of my package. Actually I bought 2 packages already as I shared with my sister. So total I did 6 jabs , she the same.

OK how do I feel? I felt I have done something for myself. I became more conscious of what I eat, what I do etc....  Hey... I've tried the whitening jab... that should account for something right? Only celebrities do it....haha.....

From the start I didn't expect a miracle, & I didn't get one. However my skin is smoother for sure- that... I'm happy. I did get fairer, but I've gotten so used to seeing myself as this lightening is a very gradual thing, so it's not so noticeable anymore. Friends noticed a difference, that's wonderful. Besides I really see it in my sister. So what they say is true, it acts better with some people than others. My sister always has lovely skin anyway, so this jab just enhanced it so much more. For me, I don't take care before, so it'll take slightly longer to get a better effect.

Someone who has done it for a long time told me-  with the whitening jab, you really need to maintain. Well I do understand. This beauty thing is gonna be costly. But as my sister puts it, it's actually only about $160- per month for maintenance, so still affordable.
She for sure is totally for maintenance as her results is so good.
Well me.....hmmm.... I'll need to persist I guess. . :)



Tuesday, 21 August 2012

Skin is noticeably smoother & fairer with the whitening jab.

Had my 4th & 5 th whitening injection during the recent holidays- National Day & Hari Raya Pusa.


These 2 jabs were doing lots of good for me.
My skin is noticeably smoother & fairer.
The 4 friends that came with me the last time, one of them has decided to do it as well!
This is contagious.
You see your friend do it with good results & you get "infected" .
It's a good thing, we can come together for the jab now.

Thursday, 2 August 2012

More on the Vitamin C, whitening injection @ Parsons Medical

Just went for my 3rd vit c jab. Went to Dr keith's new Orchard clinic.
MUch....  much...... more convenient.
Can just use the mrt.
Had arrange to meet up with friends to meet for dinner after the jab.


My friends were early so they came up to the clinic...We all packed into DR Keith's room-

After my jab, my 4 critics stared at my face & hands with approval !!!!
This time my face turned a pinkish glow. Happy!

Monday, 30 July 2012

I look brighter :) with the whitening jab

27/7/12

No time to update .......  One week later I was a bit disappointed  as I 'm not fair as snow yet!!!!....lol....... Ok that was to be expected, but still I wish I could be the special one. The effect did indeed spread out. I do notice my skin colour on my face has changed slightly, I look a little brighter. I saw my friend & she stared at me, but she couldn’t tell what changed. My boyfriend is the worst! I think I would have to put on a 100 kg before he notice anything! GUYs….
This time sis didn’t come with me as she had hers yesterday. It’s really working well on her. Maybe because her skin tone is fair to begin with. She really look different, very radiant & fair. VERY jealous. I’m a little different. The years of sun has done it’s damage. Now is a slow process of repairing!
Looking forward to my next whitening jab. Hopefully that’ll do the trick!

 

Saturday, 21 July 2012

My first experience with the Vitamin C injection for skin whitening.

Read about it, talk about it, finally did it!
Well this is my first time, it's new, it's interesting, so maybe I should just start my blog with it's review....lol.....

Book my appointment to see Dr Keith @ Parsons Medical on Friday night. Went with my sister who's just curious. Two girls were ahead of me, they were really fair! Hope it's due to the jab. I badly wanted this to work. Tired of my slightly tanned, yellowish skin from all the traveling to those sunny places...haha..... I've done my best & had dump tons on sunblock on myself, but.......

My turn.... Dr Keith is friendly like they said. My sister ask like endless questions, making me feel a little embarrass- I'm only getting a whitening jab, she make it seem as if I'm about to do heart surgery!!!! on & on she goes..... finally stopped!

Ok my turn for the jab........ Dr Keith prepared the whitening injection- & jab me , very fast procedure..... It lasted for about a minute only I think. Surprise surprise -no pain, only a small prick. So that's the "famous whitening jab". He held my both my hands & show me the difference in  tone & shade! Wow.... it's really different. The hand that he just jab has turned significantly fairer. But he reminded me lest I get too happy, that later this will spread through the body-  Well that's fine. At least it's really working!

My sister was so amused, she immediately wanted a jab as well! I ended up getting the package of 6 jabs & sharing it with my sister.